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http://hdl.handle.net/2074/1380
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| Title: | Quantitative EEG analysis for assessment to ‘plan’ a task in amyotrophic lateral sclerosis patients: a study of executive functions (planning) in ALS patients |
| Authors: | Santhosh, Jayashree
Bhatia, Manvir
Sahu, Shweta
Anand, Sneh |
| Keywords: | Amyotrophic lateral sclerosis (ALS)
Electroencephalogram (EEG)
Event-related desynchronisation (ERD)
Executive functions of brain
Brain–computer interface system (BCI) |
| Issue Date: | 2004 |
| Citation: | Cognitive Brain Research, 22(1), 59-66 |
| Abstract: | An attempt has been made to study the ability of patients with amyotrophic lateral sclerosis (ALS) to ‘plan’ a task. Electroencephalogram (EEG) data corresponding to ‘planning of a movement task’ is analyzed in comparison with a normal relaxed state. The study was conducted on 12 patients with ALS (6 males, 3 females, mean age 46.75 years) and on same number of controls (10 males, 2 females, mean age 48.75 years) to evaluate a difference in the ability to ‘plan’ a movement task between them. Patients with ALS were divided in two groups defined by unclear/clear speech. It has been observed that patients with ALS having unclear speech (Group I) showed considerable reduction (p<0.0001) in ‘planning’ a movement task, whereas patients with ALS having clear speech (Group II) showed no deficit in ‘planning’ a movement task (p=0.0577), both in comparison with age-matched controls. Apart from supporting the earlier reports of a possible extended neuronal degeneration across wide area of the fro... |
| URI: | http://eprint.iitd.ac.in/dspace/handle/2074/1380 |
| Appears in Collections: | Biomedical Engineering [CBME]
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| santhoshqua2004.pdf | | 552Kb | Adobe PDF | View/Open |
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