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Please use this identifier to cite or link to this item: http://eprint.iitd.ac.in/handle/2074/394

Title: Phase II clinical trial of a vas deferens injectable contraceptive for the male
Authors: Guha, Sujoy K
Gulshanjit Singh
Ansari, Shirfuddin
Sudheer Kumar
Srivastava, Anil
Koul, Veena
Das, H C
Malhotra, R L
Das, S K
Keywords: injectable male contraceptive
styrene maleic anhydride
pregnancy protection
Issue Date: 1997
Citation: Contraception, 56, 245-250
Abstract: Following up on an earlier clinical trial demonstrating the safety of an intra-vas deferens injection of a contraceptive drug named Risug, comprised of styrene maleic anhydride (SMA) in a solvent vehicle of dimethylsulphoxide (DMSO),a study to assess the contraceptive effectiveness of a specific dose (60 mg) of SMA bilaterally was planned and implemented, Male subjects and their wives with normal reproductive profiles were the volunteer subjects. The wives were not using any contraceptives. The results re-confirm the safety and show that for a period of at least 1 year, the treatment leads to azoospermia in the male and gives pregnancy protection.
URI: http://eprint.iitd.ac.in/dspace/handle/2074/394
Appears in Collections:Biomedical Engineering [CBME]

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