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Please use this identifier to cite or link to this item: http://eprint.iitd.ac.in/handle/2074/602

Title: Reversibility with sodium bicarbonate of styrene maleic anhydride, an intravasal injectable contraceptive, in male rats
Authors: Koul, Veena
Srivastav, Anil
Guha, Sujoy K
Keywords: contraceptive
styrene maleic anhydride (SMA)
dimethyl sulphoxide
sodium bicarbonate
Issue Date: 1998
Citation: Contraception, 58(4), 227–231
Abstract: A copolymer of styrene and maleic anhydride (SMA) was dissolved in dimethyl sulphoxide (DMSO) and injected into the lumen of the vas deferens of rats. The polymer was retained in the lumen for a period of more than 90 days.Sodium bicarbonate (10%), pH 8.9, was used to flush the polymeric material from the vas deferens lumen. The reversibility and patency of the vas deferens was thus obtained.Sodium bicarbonate proved to be an effective alternative to dimethyl sulphoxide for reversal.
URI: http://eprint.iitd.ac.in/dspace/handle/2074/602
Appears in Collections:Biomedical Engineering [CBME]

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