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dc.contributor.authorSharma, Shivani
dc.contributor.authorSen, P
dc.contributor.authorMukhopadhyay, S N
dc.contributor.authorGuha, S K
dc.date.accessioned2005-07-26T09:07:55Z
dc.date.accessioned2019-02-09T07:12:06Z
dc.date.available2005-07-26T09:07:55Z
dc.date.available2019-02-09T07:12:06Z
dc.date.issued2003
dc.identifier.citationColloids and Surfaces B: biointerfaces, 32(1), 43-50en
dc.identifier.urihttp://localhost:8080/xmlui/handle/12345678/515
dc.description.abstractRisug, a new polymeric drug with antimicrobial properties has been shown to alter the cell morphology and structure of Escherichia coli.Topographic images, traces of surface topography and analysis of surface roughness were performed, using tapping mode atomic force microscopy in air, for Risug treated as well as untreated E. coli cells.Surface roughness was quantified in terms of root mean square average of the height deviation. The treated cells indicate adhesion of Risug particles to the cell surface, particularly at the terminal ends. Damaged cells indicate flattening of the middle region and bulging at the apical ends. Marked alteration in surface roughness and cell fusion at some regions was observed.en
dc.format.extent1451681 bytes
dc.format.mimetypeapplication/pdf
dc.language.isoenen
dc.subjectRisugen
dc.subjectAFMen
dc.subjectE. colien
dc.subjectCell morphologyen
dc.subjectAntibacterial actionen
dc.titleMicrobicidal male contraceptive - risug induced morphostructural damage in e.colien
dc.typeArticleen


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