Browsing Biochemical Engg. and Biotechnology by Author "Jain, Siddhartha"
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Artificial in vivo antigen presentation by the APCs and subsequent T-cell activation: a feasibility analysis
Jain, Siddhartha (2002)Inappropriate antigen presentation by the antigenpresenting cells (APCs) is a cause of various diseases. One of the ways to combat these diseases is to immobilize the APCs near the infected tissue or a tissue which is ... -
Catalysis by ATP synthase: mechanistic, kinetic and theromodynamic characteristics
Jain, Siddhartha; Nath, Sunil (2001)Mechanistic,kinetic and thermodynamic aspects of ATP synthase have been determined and analyzed.Reversibility and inversibility of catalysis in ATP synthasis represent two contrasting modes of catalysis with important ... -
The detailed molecular mechanism of ATP synthesis in the F0 portion of ATP synthase reveals a non-chemiosmotic mode of energy coupling
Nath, Sunil; Jain, Siddhartha (2002)Based on our torsional mechanism of ion translocation, energy transduction and energy storage in ATP synthase [Curr. Sci. 75(1998) 716]; [Curr. Sci. 77 (1999) 167]; [Curr. Sci. 78 (2000) 23]; [Biochem. Biophys. Res. Commun. ... -
Kinetic model of ATP synthase: pH dependence of the rate of ATP synthesis
Jain, Siddhartha; Nath, Sunil (2000)Abstract Recently, a novel molecular mechanism of torque generation in the F0 portion of ATP synthase was proposed [Rohatgi, Saha and Nath (1998) Curr. Sci. 75, 716-718].In this mechanism, rotation of the c-subunit was ... -
Kinetic modeling of ATP synthesis by ATP synthase and Its mechanistic implications
Nath, Sunil; Jain, Siddhartha (2000)Based on the torsional mechanism of ATP synthesis by ATP synthase, a kinetic scheme has been developed in this work. The scheme considers adenine nucleotide transport, binding of substrates ADP and Pi, unbinding of product ...