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Context
A continuous process for production of d-ribulose-1,5-bisphosphate from d-glucose
Title:
A continuous process for production of d-ribulose-1,5-bisphosphate from d-glucose
Archive:
Eprints@IIT Delhi
Author(s):
Bhattacharya, Sumana
Nayaka, Amiya
Gomes, James
Bhattacharya, Sanjoy K
Nayaka, Amiya
Gomes, James
Bhattacharya, Sanjoy K
Date:
2005-08-02
Abstract:
A continuous bioprocess for production of d-ribulose-1,5-bisphosphate (RuBP) using d-glucose as starting material is described. Based on ideal plug-flow reactor modeling using kinetic parameters, a series of plug-flow reactors were designed. A cohort of enzymes namely,hexokinase, glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase (6PGDH), ribose-5-phosphate isomerase (RPI) and phosphoribulokinase, purified, immobilized and resident in five successive plug-flow reactors enables a series of conversion resulting in
an overall 60% yield of RuBP from d-glucose. Continuous conversion using this series of reactor provides a convenient route to produce RuBP in large quantities that could be used as starting material in other bioprocesses.
an overall 60% yield of RuBP from d-glucose. Continuous conversion using this series of reactor provides a convenient route to produce RuBP in large quantities that could be used as starting material in other bioprocesses.
Index terms:
Discipline(s):
RuBP production
Subject(s):
Bioreactors; Carbon dioxide fixation start-up; Immobilized enzymes
Method/Approach:
Coverage:
Publisher:
Contributors:
Source:
Language:
en
Relation:
Type:
Article
Format:
2074848 bytes
application/pdf
Copyright Information:
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